Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System

Breast cancers with a basal-like gene signature are primarily triple-negative, frequently metastatic, and carry a poor prognosis. Basal-like breast cancers are enriched for markers of breast cancer stem cells as well as markers of epithelial-mesenchymal transition (EMT). While EMT is generally thoug...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Amato, Nicholas C., Ostrander, Julie H., Bowie, Michelle L., Sistrunk, Christopher, Borowsky, Alexander, Cardiff, Robert D., Bell, Katie, Young, Lawrence J. T., Simin, Karl, Bachelder, Robin E., Delrow, Jeff, Dawson, Alyssa, Yee, Lisa D., Mrózek, Krzysztof, Clay, Timothy M., Osada, Takuya, Seewaldt, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458110/
https://www.ncbi.nlm.nih.gov/pubmed/23049838
http://dx.doi.org/10.1371/journal.pone.0045684

Ejemplares similares

Ejemplares similares