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Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity

Suppressing hyperactive endocannabinoid tone is a critical target for reducing obesity. The backbone of both endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) is the ω-6 fatty acid arachidonic acid (AA). Here we posited that excessive dietary intake of linoleic acid (LA), the precu...

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Detalles Bibliográficos
Autores principales:	Alvheim, Anita R., Malde, Marian K., Osei-Hyiaman, Douglas, Hong Lin, Yu, Pawlosky, Robert J., Madsen, Lise, Kristiansen, Karsten, Frøyland, Livar, Hibbeln, Joseph R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Integrative Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/ https://www.ncbi.nlm.nih.gov/pubmed/22334255 http://dx.doi.org/10.1038/oby.2012.38

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