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Pharmacokinetic modelling of N-(4-[(18)F]fluorobenzoyl)interleukin-2 binding to activated lymphocytes in an xenograft model of inflammation

PURPOSE: N-(4-[(18)F]Fluorobenzoyl)interleukin-2 ([(18)F]FB-IL2) specifically binds to interleukin-2 receptors (IL-2R) and thus may be used to detect inflammation processes using positron emission tomography (PET). We now validated whether [(18)F]FB-IL2 can be used to quantify activated human periph...

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Detalles Bibliográficos
Autores principales:	Di Gialleonardo, Valentina, Signore, Alberto, Willemsen, Antoon T. M., Sijbesma, Jurgen W. A., Dierckx, Rudi A. J. O., de Vries, Erik F. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458201/ https://www.ncbi.nlm.nih.gov/pubmed/22777334 http://dx.doi.org/10.1007/s00259-012-2176-y

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