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D-Serine Production, Degradation, and Transport in ALS: Critical Role of Methodology

In mammalian systems, D-serine is perhaps the most biologically active D-amino acid described to date. D-serine is a coagonist at the NMDA-receptor, and receptor activation is dependent on D-serine binding. Because D-serine binding dramatically increases receptor affinity for glutamate, it can produ...

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Detalles Bibliográficos
Autores principales:	Crow, John P., Marecki, John C., Thompson, Misty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458282/ https://www.ncbi.nlm.nih.gov/pubmed/23029613 http://dx.doi.org/10.1155/2012/625245

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