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Integrative analysis of gene and miRNA expression profiles with transcription factor–miRNA feed-forward loops identifies regulators in human cancers
We describe here a novel method for integrating gene and miRNA expression profiles in cancer using feed-forward loops (FFLs) consisting of transcription factors (TFs), miRNAs and their common target genes. The dChip-GemiNI (Gene and miRNA Network-based Integration) method statistically ranks computa...
Autores principales: | Yan, Zhenyu, Shah, Parantu K., Amin, Samir B., Samur, Mehmet K., Huang, Norman, Wang, Xujun, Misra, Vikas, Ji, Hongbin, Gabuzda, Dana, Li, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458521/ https://www.ncbi.nlm.nih.gov/pubmed/22645320 http://dx.doi.org/10.1093/nar/gks395 |
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