Quantifying selection in high-throughput Immunoglobulin sequencing data sets

High-throughput immunoglobulin sequencing promises new insights into the somatic hypermutation and antigen-driven selection processes that underlie B-cell affinity maturation and adaptive immunity. The ability to estimate positive and negative selection from these sequence data has broad application...

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Detalles Bibliográficos
Autores principales: Yaari, Gur, Uduman, Mohamed, Kleinstein, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458526/
https://www.ncbi.nlm.nih.gov/pubmed/22641856
http://dx.doi.org/10.1093/nar/gks457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458526/
https://www.ncbi.nlm.nih.gov/pubmed/22641856
http://dx.doi.org/10.1093/nar/gks457

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