Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Despite the promise of RNA interference (RNAi) and its potential, e.g. for use in cancer therapy, several technical obstacles must first be overcome. The major hurdle of RNAi-based therapeutics is to deliver nucleic acids across the cell’s plasma membrane. This study demonstrates that exosome vesicl...

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Detalles Bibliográficos
Autores principales: Wahlgren, Jessica, Karlson, Tanya De L., Brisslert, Mikael, Vaziri Sani, Forugh, Telemo, Esbjörn, Sunnerhagen, Per, Valadi, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458529/
https://www.ncbi.nlm.nih.gov/pubmed/22618874
http://dx.doi.org/10.1093/nar/gks463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458529/
https://www.ncbi.nlm.nih.gov/pubmed/22618874
http://dx.doi.org/10.1093/nar/gks463

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