YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts

The human Y box-binding protein-1 (YB-1) is a deoxyribonucleic acid (DNA)/ribonucleic acid (RNA)-binding protein with pleiotropic functions. Besides its roles in the regulation of transcription and translation, several recent studies indicate that YB-1 is a spliceosome-associated protein and is invo...

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Detalles Bibliográficos
Autores principales: Wei, Wen-Juan, Mu, Shi-Rong, Heiner, Monika, Fu, Xing, Cao, Li-Juan, Gong, Xiu-Feng, Bindereif, Albrecht, Hui, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458536/
https://www.ncbi.nlm.nih.gov/pubmed/22730292
http://dx.doi.org/10.1093/nar/gks579

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