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Chronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cells
UV radiation induces two major types of DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine–pyrimidine photoproducts, which are both primarily repaired by nucleotide excision repair (NER). Here, we investigated how chronic low-dose UV (CLUV)-induced mutagenesis occurs in rad14Δ NER-...
Autores principales: | Haruta, Nami, Kubota, Yoshino, Hishida, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458537/ https://www.ncbi.nlm.nih.gov/pubmed/22743272 http://dx.doi.org/10.1093/nar/gks580 |
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