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The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson, RAPADILINO and Baller–Gerold syndromes. Mouse models and experiments in human and Xenopus have proven the N-terminal part of RecQL4 to be vital f...

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Detalles Bibliográficos
Autores principales:	Ohlenschläger, Oliver, Kuhnert, Anja, Schneider, Annerose, Haumann, Sebastian, Bellstedt, Peter, Keller, Heidi, Saluz, Hans-Peter, Hortschansky, Peter, Hänel, Frank, Grosse, Frank, Görlach, Matthias, Pospiech, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458545/ https://www.ncbi.nlm.nih.gov/pubmed/22730300 http://dx.doi.org/10.1093/nar/gks591

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