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Modular control of multiple pathways using engineered orthogonal T7 polymerases

Synthetic genetic sensors and circuits enable programmable control over the timing and conditions of gene expression. They are being increasingly incorporated into the control of complex, multigene pathways and cellular functions. Here, we propose a design strategy to genetically separate the sensin...

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Detalles Bibliográficos
Autores principales: Temme, Karsten, Hill, Rena, Segall-Shapiro, Thomas H., Moser, Felix, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458549/
https://www.ncbi.nlm.nih.gov/pubmed/22743271
http://dx.doi.org/10.1093/nar/gks597

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