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Modular control of multiple pathways using engineered orthogonal T7 polymerases
Synthetic genetic sensors and circuits enable programmable control over the timing and conditions of gene expression. They are being increasingly incorporated into the control of complex, multigene pathways and cellular functions. Here, we propose a design strategy to genetically separate the sensin...
Autores principales: | Temme, Karsten, Hill, Rena, Segall-Shapiro, Thomas H., Moser, Felix, Voigt, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458549/ https://www.ncbi.nlm.nih.gov/pubmed/22743271 http://dx.doi.org/10.1093/nar/gks597 |
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