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p21 promotes error-free replication-coupled DNA double-strand break repair
p21 is a well-established regulator of cell cycle progression. The role of p21 in DNA repair, however, remains poorly characterized. Here, we describe a critical role of p21 in a replication-coupled DNA double-strand break (DSB) repair that is mechanistically distinct from its cell cycle checkpoint...
Autores principales: | Mauro, Maurizio, Rego, Meghan A., Boisvert, Rebecca A., Esashi, Fumiko, Cavallo, Francesca, Jasin, Maria, Howlett, Niall G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458556/ https://www.ncbi.nlm.nih.gov/pubmed/22735704 http://dx.doi.org/10.1093/nar/gks612 |
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