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A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

Streptomyces davawensis is the only organism known to synthesize the antibiotic roseoflavin, a riboflavin (vitamin B(2)) analog. Roseoflavin is converted to roseoflavin mononucleotide (RoFMN) and roseoflavin adenine dinucleotide in the cytoplasm of target cells. (Ribo-)Flavin mononucleotide (FMN) ri...

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Detalles Bibliográficos
Autores principales:	Pedrolli, Danielle Biscaro, Matern, Andreas, Wang, Joy, Ester, Miriam, Siedler, Kathrin, Breaker, Ronald, Mack, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458559/ https://www.ncbi.nlm.nih.gov/pubmed/22740651 http://dx.doi.org/10.1093/nar/gks616

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