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Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U(6)A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting

Programmed −1 ribosomal frameshifting is employed in the expression of a number of viral and cellular genes. In this process, the ribosome slips backwards by a single nucleotide and continues translation of an overlapping reading frame, generating a fusion protein. Frameshifting signals comprise a h...

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Detalles Bibliográficos
Autores principales:	Lin, Zhaoru, Gilbert, Robert J. C., Brierley, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458567/ https://www.ncbi.nlm.nih.gov/pubmed/22743270 http://dx.doi.org/10.1093/nar/gks629

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