Cargando…

Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U(6)A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting

Programmed −1 ribosomal frameshifting is employed in the expression of a number of viral and cellular genes. In this process, the ribosome slips backwards by a single nucleotide and continues translation of an overlapping reading frame, generating a fusion protein. Frameshifting signals comprise a h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Zhaoru, Gilbert, Robert J. C., Brierley, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458567/ https://www.ncbi.nlm.nih.gov/pubmed/22743270 http://dx.doi.org/10.1093/nar/gks629

Ejemplares similares

Stimulation of ribosomal frameshifting by RNA G-quadruplex structures
por: Yu, Chien-Hung, et al.
Publicado: (2014)

Antisense-induced ribosomal frameshifting
por: Henderson, Clark M., et al.
Publicado: (2006)

RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus
por: Ishimaru, Daniella, et al.
Publicado: (2013)

Stimulation of ribosomal frameshifting by antisense LNA
por: Yu, Chien-Hung, et al.
Publicado: (2010)

Interaction of the HIV-1 frameshift signal with the ribosome
por: Mazauric, Marie-Hélène, et al.
Publicado: (2009)

Endogenous ribosomal frameshift signals operate as mRNA destabilizing elements through at least two molecular pathways in yeast
por: Belew, Ashton T., et al.
Publicado: (2011)

HIV-1 frameshift efficiency is primarily determined by the stability of base pairs positioned at the mRNA entrance channel of the ribosome
por: Mouzakis, Kathryn D., et al.
Publicado: (2013)

Stem–loop structures can effectively substitute for an RNA pseudoknot in −1 ribosomal frameshifting
por: Yu, Chien-Hung, et al.
Publicado: (2011)

The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed –1 ribosomal frameshifting
por: Liao, Pei-Yu, et al.
Publicado: (2011)

Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus
por: Napthine, Sawsan, et al.
Publicado: (2019)

Investigating molecular mechanisms of 2A-stimulated ribosomal pausing and frameshifting in Theilovirus
por: Hill, Chris H, et al.
Publicado: (2021)

An intermolecular RNA triplex provides insight into structural determinants for the pseudoknot stimulator of −1 ribosomal frameshifting
por: Chou, Ming-Yuan, et al.
Publicado: (2010)

Functional analysis of the SRV-1 RNA frameshifting pseudoknot
por: Olsthoorn, René C. L., et al.
Publicado: (2010)

FSscan: a mechanism-based program to identify +1 ribosomal frameshift hotspots
por: Liao, Pei-Yu, et al.
Publicado: (2009)

EF-G catalyzed translocation dynamics in the presence of ribosomal frameshifting stimulatory signals
por: Kim, Hee-Kyung, et al.
Publicado: (2017)

The role of RNA pseudoknot stem 1 length in the promotion of efficient −1 ribosomal frameshifting
por: Napthine, Sawsan, et al.
Publicado: (1999)

A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting
por: Namy, Olivier, et al.
Publicado: (2006)

Expression of a coronavirus ribosomal frameshift signal in Escherichia coli: influence of tRNA anticodon modification on frameshifting
por: Brierley, Ian, et al.
Publicado: (1997)

The gateway pDEST17 expression vector encodes a −1 ribosomal frameshifting sequence
por: Belfield, Eric J., et al.
Publicado: (2007)

The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift
por: Léger, Mélissa, et al.
Publicado: (2007)

Ensemble simulations: folding, unfolding and misfolding of a high-efficiency frameshifting RNA pseudoknot
por: Q. Nguyen, Khai K., et al.
Publicado: (2017)

V, 2.Ribosomal frameshifting in astroviruses
por: Brierley, Ian, et al.
Publicado: (2003)

Characterization of the frameshift signal of Edr, a mammalian example of programmed −1 ribosomal frameshifting
por: Manktelow, Emily, et al.
Publicado: (2005)

Coordination among tertiary base pairs results in an efficient frameshift-stimulating RNA pseudoknot
por: Chen, Yu-Ting, et al.
Publicado: (2017)

Multiple Cis-acting elements modulate programmed -1 ribosomal frameshifting in Pea enation mosaic virus
por: Gao, Feng, et al.
Publicado: (2016)

Characterization of an efficient coronavirus ribosomal frameshifting signal: Requirement for an RNA pseudoknot
por: Brierley, Ian, et al.
Publicado: (1989)

A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting
por: Liao, Pei-Yu, et al.
Publicado: (2008)

Twice exploration of tRNA +1 frameshifting in an elongation cycle of protein synthesis
por: Gamper, Howard, et al.
Publicado: (2021)

-1 Programmed ribosomal frameshifting in Class 2 umbravirus-like RNAs uses multiple long-distance interactions to shift between active and inactive structures and destabilize the frameshift stimulating element
por: Mikkelsen, Anna A, et al.
Publicado: (2023)

Mutational analysis of the RNA pseudoknot component of a coronavirus ribosomal frameshifting signal()
por: Brierley, Ian, et al.
Publicado: (1991)

The presence of the TAR RNA structure alters the programmed -1 ribosomal frameshift efficiency of the human immunodeficiency virus type 1 (HIV-1) by modifying the rate of translation initiation
por: Gendron, Karine, et al.
Publicado: (2008)

Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting
por: Caliskan, Neva, et al.
Publicado: (2015)

The role of wobble uridine modifications in +1 translational frameshifting in eukaryotes
por: Tükenmez, Hasan, et al.
Publicado: (2015)

Programmed −1 ribosomal frameshifting from the perspective of the conformational dynamics of mRNA and ribosomes
por: Chang, Kai-Chun, et al.
Publicado: (2021)

The Q-base of asparaginyl-tRNA is dispensable for efficient −1 ribosomal frameshifting in eukaryotes
por: Marczinke, Beate, et al.
Publicado: (2000)

Evidence for an RNA pseudoknot loop-helix interaction essential for efficient −1 ribosomal frameshifting
por: Liphardt, Jan, et al.
Publicado: (1999)

An astrovirus frameshift signal induces ribosomal frameshifting in vitro
por: Lewis, T. L., et al.
Publicado: (1995)

Pseudoknot-Dependent Programmed —1 Ribosomal Frameshifting: Structures, Mechanisms and Models
por: Brierley, Ian, et al.
Publicado: (2009)

Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding
por: Loughran, Gary, et al.
Publicado: (2022)

Intricacies of ribosomal frameshifting
por: Atkins, John F., et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_j20oc75ik4uof1cn5ufe75vq2m