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Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase

Fanconi anemia (FA) pathway members, FANCD2 and FANCI, contribute to the repair of replication-stalling DNA lesions. FA pathway activation relies on phosphorylation of FANCI by the ataxia telangiectasia and Rad3-related (ATR) kinase, followed by monoubiquitination of FANCD2 and FANCI by the FA core...

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Detalles Bibliográficos
Autores principales:	Sareen, Archana, Chaudhury, Indrajit, Adams, Nicole, Sobeck, Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458572/ https://www.ncbi.nlm.nih.gov/pubmed/22753026 http://dx.doi.org/10.1093/nar/gks638

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