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The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome
MacroH2A is a histone H2A variant that is typically found in heterochromatic regions of the genome. A positively charged linker that connects the histone-fold with the macro-domain was suggested to have DNA-binding properties, and has been shown to promote oligomerization of chromatin fibers. Here w...
Autores principales: | Chakravarthy, Srinivas, Patel, Ashok, Bowman, Gregory D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458575/ https://www.ncbi.nlm.nih.gov/pubmed/22753032 http://dx.doi.org/10.1093/nar/gks645 |
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