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Synthesis of a library of tricyclic azepinoisoindolinones

Hydrozirconation of 1-hexyne, the addition to in situ prepared N-acyliminium species, and ring-closing metathesis (RCM) were key steps in the preparation of a tricyclic isoindolinone scaffold. An unusual alkene isomerization process during the RCM was identified and studied in some detail. Chemical...

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Detalles Bibliográficos
Autores principales:	Miller, Bettina, Mao, Shuli, Rosenker, Kara M George, Pierce, Joshua G, Wipf, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2012
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458725/ https://www.ncbi.nlm.nih.gov/pubmed/23019435 http://dx.doi.org/10.3762/bjoc.8.120

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