Partial thioamide scan on the lipopeptaibiotic trichogin GA IV. Effects on folding and bioactivity

Backbone modification is a common chemical tool to control the conformation of linear peptides and to explore potentially useful effects on their biochemical and biophysical properties. The thioamide, ψ[CS-NH], group is a nearly isosteric structural mimic of the amide (peptide) functionality. In thi...

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Detalles Bibliográficos
Autores principales: De Zotti, Marta, Biondi, Barbara, Peggion, Cristina, De Poli, Matteo, Fathi, Haleh, Oancea, Simona, Toniolo, Claudio, Formaggio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458734/
https://www.ncbi.nlm.nih.gov/pubmed/23019444
http://dx.doi.org/10.3762/bjoc.8.129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458734/
https://www.ncbi.nlm.nih.gov/pubmed/23019444
http://dx.doi.org/10.3762/bjoc.8.129

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