Synthesis of diverse indole libraries on polystyrene resin – Scope and limitations of an organometallic reaction on solid supports

The synthesis of diverse substituted indole structures on solid supports is described. The immobilization of nitrobenzoic acid onto Merrifield resin and the subsequent treatment with alkenyl Grignard reagents delivered indole carboxylates bound to solid supports. In contrast to results in the liquid...

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Detalles Bibliográficos
Autores principales: Knepper, Kerstin, Vanderheiden, Sylvia, Bräse, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458737/
https://www.ncbi.nlm.nih.gov/pubmed/23019447
http://dx.doi.org/10.3762/bjoc.8.132