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A novel asymmetric synthesis of cinacalcet hydrochloride
A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458763/ https://www.ncbi.nlm.nih.gov/pubmed/23019473 http://dx.doi.org/10.3762/bjoc.8.158 |
| _version_ | 1782244697483247616 |
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| author | Arava, Veera R Gorentla, Laxminarasimhulu Dubey, Pramod K |
| author_facet | Arava, Veera R Gorentla, Laxminarasimhulu Dubey, Pramod K |
| author_sort | Arava, Veera R |
| collection | PubMed |
| description | A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described. |
| format | Online Article Text |
| id | pubmed-3458763 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-34587632012-09-27 A novel asymmetric synthesis of cinacalcet hydrochloride Arava, Veera R Gorentla, Laxminarasimhulu Dubey, Pramod K Beilstein J Org Chem Letter A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described. Beilstein-Institut 2012-08-24 /pmc/articles/PMC3458763/ /pubmed/23019473 http://dx.doi.org/10.3762/bjoc.8.158 Text en Copyright © 2012, Arava et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Letter Arava, Veera R Gorentla, Laxminarasimhulu Dubey, Pramod K A novel asymmetric synthesis of cinacalcet hydrochloride |
| title | A novel asymmetric synthesis of cinacalcet hydrochloride |
| title_full | A novel asymmetric synthesis of cinacalcet hydrochloride |
| title_fullStr | A novel asymmetric synthesis of cinacalcet hydrochloride |
| title_full_unstemmed | A novel asymmetric synthesis of cinacalcet hydrochloride |
| title_short | A novel asymmetric synthesis of cinacalcet hydrochloride |
| title_sort | novel asymmetric synthesis of cinacalcet hydrochloride |
| topic | Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458763/ https://www.ncbi.nlm.nih.gov/pubmed/23019473 http://dx.doi.org/10.3762/bjoc.8.158 |
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