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The Leukemia-Associated Fusion Protein MN1-TEL Blocks TEL-Specific Recognition Sequences

The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that ∼20% of GFP-tagged MN1 and TEL is transiently immobilised, likely due to indirec...

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Detalles Bibliográficos
Autores principales: ter Haar, W. Martijn, Meester-Smoor, Magda A., van Wely, Karel H. M., Schot, Claudia C. M. M., Janssen, Marjolein J. F. W., Geverts, Bart, Bonten, Jacqueline, Grosveld, Gerard C., Houtsmuller, Adriaan B., Zwarthoff, Ellen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458806/
https://www.ncbi.nlm.nih.gov/pubmed/23049943
http://dx.doi.org/10.1371/journal.pone.0046085