An Opposite Effect of the CDK Inhibitor, p18(INK4c) on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells

Self-renewal is a feature common to both adult and embryonic stem (ES) cells, as well as tumor stem cells (TSCs). The cyclin-dependent kinase inhibitor, p18(INK4c), is a known tumor suppressor that can inhibit self-renewal of tumor cells or adult stem cells. Here, we demonstrate an opposite effect o...

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Detalles Bibliográficos
Autores principales: Li, Yanxin, Pal, Rekha, Sung, Li-Ying, Feng, Haizhong, Miao, Weimin, Cheng, Shi-Yuan, Tian, Cindy, Cheng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458833/
https://www.ncbi.nlm.nih.gov/pubmed/23049777
http://dx.doi.org/10.1371/journal.pone.0045212

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