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Phenylalanine Hydroxylase from Legionella pneumophila Is a Thermostable Enzyme with a Major Functional Role in Pyomelanin Synthesis
BACKGROUND: Legionella pneumophila is a pathogenic bacterium that can cause Legionnaires’ disease and other non-pneumonic infections in humans. This bacterium produces a pyomelanin pigment, a potential virulence factor with ferric reductase activity. In this work, we have investigated the role of ph...
Autores principales: | Flydal, Marte I., Chatfield, Christa H., Zheng, Huaixin, Gunderson, Felizza F., Aubi, Oscar, Cianciotto, Nicholas P., Martinez, Aurora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458870/ https://www.ncbi.nlm.nih.gov/pubmed/23049981 http://dx.doi.org/10.1371/journal.pone.0046209 |
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