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Humanization and Characterization of an Anti-Ricin Neutralization Monoclonal Antibody

Ricin is regarded as a high terrorist risk for the public due to its high toxicity and ease of production. Currently, there is no therapeutic or vaccine available against ricin. D9, a murine monoclonal antibody developed previously in our laboratory, can strongly neutralize ricin and is therefore a...

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Detalles Bibliográficos
Autores principales: Hu, Wei-Gang, Yin, Junfei, Chau, Damon, Negrych, Laurel M., Cherwonogrodzky, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458913/
https://www.ncbi.nlm.nih.gov/pubmed/23049820
http://dx.doi.org/10.1371/journal.pone.0045595