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Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns

BACKGROUND: Ficolin-2 coded by FCN2 gene is a soluble serum protein and an innate immune recognition element of the complement system. FCN2 gene polymorphisms reveal distinct geographical patterns and are documented to alter serum ficolin levels and modulate disease susceptibility. METHODS: We emplo...

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Detalles Bibliográficos
Autores principales: Ojurongbe, Olusola, Ouf, Eman Abou, Van Tong, Hoang, Toan, Nguyen L, Song, Le H, Luz, Paola R, Messias-Reason, Iara JT, Nurjadi, Dennis, Zanger, Philipp, Kun, Jürgen FJ, Kremsner, Peter G, Velavan, Thirumalaisamy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458960/
https://www.ncbi.nlm.nih.gov/pubmed/22594803
http://dx.doi.org/10.1186/1471-2350-13-37