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Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients

BACKGROUND: The enzymes of the cytochrome P450 family (CYPs) play an important role in the metabolism of a great variety of anticancer agents; therefore, polymorphisms in genes encoding for metabolizing enzymes and drugs transporters can affect drug efficacy and toxicity. METHODS: The genetic polymo...

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Detalles Bibliográficos
Autores principales:	Seredina, Tatyana A, Goreva, Olga B, Talaban, Valeria O, Grishanova, Alevtina Yu, Lyakhovich, Vyacheslav V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458973/ https://www.ncbi.nlm.nih.gov/pubmed/22702493 http://dx.doi.org/10.1186/1471-2350-13-45

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