Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis

Nascent polypeptides entering the endoplasmic reticulum (ER) are covalently modified with pre-assembled oligosaccharides. The terminal glucose and mannose residues are immediately removed after transfer of the oligosaccharide onto newly synthesized polypeptides. This processing determines whether th...

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Detalles Bibliográficos
Autores principales: Hebert, Daniel N., Molinari, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459134/
https://www.ncbi.nlm.nih.gov/pubmed/22921611
http://dx.doi.org/10.1016/j.tibs.2012.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459134/
https://www.ncbi.nlm.nih.gov/pubmed/22921611
http://dx.doi.org/10.1016/j.tibs.2012.07.005

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