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A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature

A case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrall...

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Autores principales: Ariizumi, Yasushi, Koizumi, Hirotaka, Hoshikawa, Masahiro, Shinmyo, Takuo, Ando, Kouji, Mochizuki, Atsushi, Tateishi, Ayako, Doi, Masatomo, Funatsu, Mieko, Maeda, Ichirou, Takagi, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459257/
https://www.ncbi.nlm.nih.gov/pubmed/23050181
http://dx.doi.org/10.1155/2012/782304
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author Ariizumi, Yasushi
Koizumi, Hirotaka
Hoshikawa, Masahiro
Shinmyo, Takuo
Ando, Kouji
Mochizuki, Atsushi
Tateishi, Ayako
Doi, Masatomo
Funatsu, Mieko
Maeda, Ichirou
Takagi, Masayuki
author_facet Ariizumi, Yasushi
Koizumi, Hirotaka
Hoshikawa, Masahiro
Shinmyo, Takuo
Ando, Kouji
Mochizuki, Atsushi
Tateishi, Ayako
Doi, Masatomo
Funatsu, Mieko
Maeda, Ichirou
Takagi, Masayuki
author_sort Ariizumi, Yasushi
collection PubMed
description A case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrally located nucleus, a clear cytoplasm, and apparent cell borders. The tumor also showed a focally hemangiopericytomatous pattern with irregularly branching or dilated vessels. Electron microscopy revealed smooth muscle differentiation of the tumor cells. Immunostaining further revealed that the tumor cells expressed smooth muscle actin, h-caldesmon, muscle specific actin (HHF-35), but not cytokeratin, epithelial membrane antigen, synaptophysin, or chromogranin A. Based on these findings, a diagnosis of primary pulmonary glomus tumor was established. Glomus tumors of the lung are very rare and only 21 cases have been reported to date. The histological features of the present tumor and the relevant literature are discussed.
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spelling pubmed-34592572012-10-03 A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature Ariizumi, Yasushi Koizumi, Hirotaka Hoshikawa, Masahiro Shinmyo, Takuo Ando, Kouji Mochizuki, Atsushi Tateishi, Ayako Doi, Masatomo Funatsu, Mieko Maeda, Ichirou Takagi, Masayuki Case Rep Pathol Case Report A case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrally located nucleus, a clear cytoplasm, and apparent cell borders. The tumor also showed a focally hemangiopericytomatous pattern with irregularly branching or dilated vessels. Electron microscopy revealed smooth muscle differentiation of the tumor cells. Immunostaining further revealed that the tumor cells expressed smooth muscle actin, h-caldesmon, muscle specific actin (HHF-35), but not cytokeratin, epithelial membrane antigen, synaptophysin, or chromogranin A. Based on these findings, a diagnosis of primary pulmonary glomus tumor was established. Glomus tumors of the lung are very rare and only 21 cases have been reported to date. The histological features of the present tumor and the relevant literature are discussed. Hindawi Publishing Corporation 2012 2012-09-19 /pmc/articles/PMC3459257/ /pubmed/23050181 http://dx.doi.org/10.1155/2012/782304 Text en Copyright © 2012 Yasushi Ariizumi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ariizumi, Yasushi
Koizumi, Hirotaka
Hoshikawa, Masahiro
Shinmyo, Takuo
Ando, Kouji
Mochizuki, Atsushi
Tateishi, Ayako
Doi, Masatomo
Funatsu, Mieko
Maeda, Ichirou
Takagi, Masayuki
A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title_full A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title_fullStr A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title_full_unstemmed A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title_short A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
title_sort primary pulmonary glomus tumor: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459257/
https://www.ncbi.nlm.nih.gov/pubmed/23050181
http://dx.doi.org/10.1155/2012/782304
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