A direct characterization of human mutation based on microsatellites

Mutations are the raw material of evolution, but have been difficult to study directly. We report the largest study of new mutations to date: 2,058 germline changes discovered by analyzing 85,289 Icelanders at 2,477 microsatellites. The paternal-to-maternal mutation rate ratio is 3.3, and the rate i...

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Detalles Bibliográficos
Autores principales: Sun, James X., Helgason, Agnar, Masson, Gisli, Ebenesersdóttir, Sigríđur Sunna, Li, Heng, Mallick, Swapan, Gnerre, Sante, Patterson, Nick, Kong, Augustine, Reich, David, Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459271/
https://www.ncbi.nlm.nih.gov/pubmed/22922873
http://dx.doi.org/10.1038/ng.2398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459271/
https://www.ncbi.nlm.nih.gov/pubmed/22922873
http://dx.doi.org/10.1038/ng.2398

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