Imatinib resistance: a review of alternative inhibitors in chronic myeloid leukemia

The development of point mutations in the BCR-ABL kinase domain is the main reason for imatinib resistance in chronic myeloid leukemia. Different detection methods are used in chronic myeloid leukemia monitoring, such as direct sequencing, denaturing high performance liquid chromatography and allele...

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Detalles Bibliográficos
Autores principales: Bitencourt, Roberta, Zalcberg, Ilana, Louro, Iúri Drumond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459369/
https://www.ncbi.nlm.nih.gov/pubmed/23049365
http://dx.doi.org/10.5581/1516-8484.20110124

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