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Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia

Acute promyelocytic leukemia is characterized by gene rearrangements that always involve the retinoic acid receptor alpha on chromosome 15. In the majority of patients t(15;17) is detected, which generates the promyelocytic leukemia gene/retinoic acid receptor alpha rearrangement. This rearrangement...

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Detalles Bibliográficos
Autores principales: Bassi, Sarah Cristina, Rego, Eduardo Magalhães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459394/
https://www.ncbi.nlm.nih.gov/pubmed/23049403
http://dx.doi.org/10.5581/1516-8484.20120033

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