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Modeling the Chronotropic Effect of Isoprenaline on Rabbit Sinoatrial Node

Introduction: β-adrenergic stimulation increases the heart rate by accelerating the electrical activity of the pacemaker of the heart, the sinoatrial node (SAN). Ionic mechanisms underlying the actions of β-adrenergic stimulation are not yet fully understood. Isoprenaline (ISO), a β-adrenoceptor ago...

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Detalles Bibliográficos
Autores principales:	Zhang, Henggui, Butters, Timothy, Adeniran, Ismail, Higham, Jonathan, Holden, Arun V., Boyett, Mark R., Hancox, Jules C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459472/ https://www.ncbi.nlm.nih.gov/pubmed/23060799 http://dx.doi.org/10.3389/fphys.2012.00241

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