Cargando…
Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap
A 19-year-old male presented with persistent macroscopic hematuria for last 3 months. On initial evaluation, he was found to have minimal proteinuria, normal renal function, and normal complement with negative lupus serology. Light microscopy, immunofluorescence and electron microscopy of renal tiss...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459526/ https://www.ncbi.nlm.nih.gov/pubmed/23087557 http://dx.doi.org/10.4103/0971-4065.98761 |
_version_ | 1782244813739917312 |
---|---|
author | Mandal, S. N. Jha, R. Fatima, R. Swarnalata, G. |
author_facet | Mandal, S. N. Jha, R. Fatima, R. Swarnalata, G. |
author_sort | Mandal, S. N. |
collection | PubMed |
description | A 19-year-old male presented with persistent macroscopic hematuria for last 3 months. On initial evaluation, he was found to have minimal proteinuria, normal renal function, and normal complement with negative lupus serology. Light microscopy, immunofluorescence and electron microscopy of renal tissue confirmed the presence of C1q nephropathy. Because of poor response to immunosuppressive agent (prednisolone and mycophenolate mofetil), passage of urinary clot once and vexing persistent macroscopic hematuria, alternative diagnosis was considered. Cystourethroscopy showed urethritis of prostatic urethra. Immunosuppressives were stopped and doxycycline started to which hematuria responded dramatically. This case report illustrates that hematuria in this patient was because of undiagnosed urethritis rather than incidental C1q nephropathy. |
format | Online Article Text |
id | pubmed-3459526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34595262012-10-19 Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap Mandal, S. N. Jha, R. Fatima, R. Swarnalata, G. Indian J Nephrol Case Report A 19-year-old male presented with persistent macroscopic hematuria for last 3 months. On initial evaluation, he was found to have minimal proteinuria, normal renal function, and normal complement with negative lupus serology. Light microscopy, immunofluorescence and electron microscopy of renal tissue confirmed the presence of C1q nephropathy. Because of poor response to immunosuppressive agent (prednisolone and mycophenolate mofetil), passage of urinary clot once and vexing persistent macroscopic hematuria, alternative diagnosis was considered. Cystourethroscopy showed urethritis of prostatic urethra. Immunosuppressives were stopped and doxycycline started to which hematuria responded dramatically. This case report illustrates that hematuria in this patient was because of undiagnosed urethritis rather than incidental C1q nephropathy. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3459526/ /pubmed/23087557 http://dx.doi.org/10.4103/0971-4065.98761 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mandal, S. N. Jha, R. Fatima, R. Swarnalata, G. Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title | Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title_full | Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title_fullStr | Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title_full_unstemmed | Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title_short | Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap |
title_sort | non-nephronal hematuria misdiagnosed as c1q nephropathy: look before you leap |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459526/ https://www.ncbi.nlm.nih.gov/pubmed/23087557 http://dx.doi.org/10.4103/0971-4065.98761 |
work_keys_str_mv | AT mandalsn nonnephronalhematuriamisdiagnosedasc1qnephropathylookbeforeyouleap AT jhar nonnephronalhematuriamisdiagnosedasc1qnephropathylookbeforeyouleap AT fatimar nonnephronalhematuriamisdiagnosedasc1qnephropathylookbeforeyouleap AT swarnalatag nonnephronalhematuriamisdiagnosedasc1qnephropathylookbeforeyouleap |