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Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation

OBJECTIVES: To investigate the effectiveness of respiratory physiotherapy based on clinical evidence and analyze the improvement in respiratory parameters. METHODS: A prospective study was carried out in the Bone Marrow Transplant Unit of the Universidade Estadual de Campinas (UNICAMP). Two differen...

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Autores principales: Bom, Eliane Aparecida, de Souza, Clarissa Vasconcelos, Thiesen, Rosana Almeida da Silva, Miranda, Eliana Cristina Martins, de Souza, Carmino Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459632/
https://www.ncbi.nlm.nih.gov/pubmed/23049417
http://dx.doi.org/10.5581/1516-8484.20120047
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author Bom, Eliane Aparecida
de Souza, Clarissa Vasconcelos
Thiesen, Rosana Almeida da Silva
Miranda, Eliana Cristina Martins
de Souza, Carmino Antonio
author_facet Bom, Eliane Aparecida
de Souza, Clarissa Vasconcelos
Thiesen, Rosana Almeida da Silva
Miranda, Eliana Cristina Martins
de Souza, Carmino Antonio
author_sort Bom, Eliane Aparecida
collection PubMed
description OBJECTIVES: To investigate the effectiveness of respiratory physiotherapy based on clinical evidence and analyze the improvement in respiratory parameters. METHODS: A prospective study was carried out in the Bone Marrow Transplant Unit of the Universidade Estadual de Campinas (UNICAMP). Two different previously established respiratory physiotherapy protocols were applied from days D-1 to D+7 that aimed to improve airway clearance, pulmonary re-expansion and the strengthening of respiratory muscles. Group A were subjected to diaphragmatic proprioceptive stimulation, breathing exercises, incentive spirometry with Respiron(®), inspiratory muscle training with the Threshold(®) Inspiratory Muscle Training device, bronchial hygienization with Shaker(®) and cough stimulation. Group B performed a protocol that only used incentive spirometry. The parameters analyzed were: tidal volume, minute volume, maximal inspiratory pressure, maximal expiratory pressure, oxygen saturation, heart rate and respiratory frequency. RESULTS: Sixty-seven patients submitted to myeloablative hematopoietic stem cell transplantation were included in this study. Among these, thirty-nine were evaluated and randomized in the two groups. There were significant differences between the groups for tidal volume at D+2 (p-value = 0.007) and maximal inspiratory pressure (p-value = 0.03), maximal expiratory pressure (p-value = 0.03) and tidal volume (p-value = 0.004) at D+7. CONCLUSIONS: On comparing Group A with Group B, the authors concluded that the protocol of respiratory physiotherapy applied in this study resulted in an improvement in ventilation and in respiratory muscle strength of patients submitted to hematopoietic stem cell transplantation.
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spelling pubmed-34596322012-10-04 Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation Bom, Eliane Aparecida de Souza, Clarissa Vasconcelos Thiesen, Rosana Almeida da Silva Miranda, Eliana Cristina Martins de Souza, Carmino Antonio Rev Bras Hematol Hemoter Original Article OBJECTIVES: To investigate the effectiveness of respiratory physiotherapy based on clinical evidence and analyze the improvement in respiratory parameters. METHODS: A prospective study was carried out in the Bone Marrow Transplant Unit of the Universidade Estadual de Campinas (UNICAMP). Two different previously established respiratory physiotherapy protocols were applied from days D-1 to D+7 that aimed to improve airway clearance, pulmonary re-expansion and the strengthening of respiratory muscles. Group A were subjected to diaphragmatic proprioceptive stimulation, breathing exercises, incentive spirometry with Respiron(®), inspiratory muscle training with the Threshold(®) Inspiratory Muscle Training device, bronchial hygienization with Shaker(®) and cough stimulation. Group B performed a protocol that only used incentive spirometry. The parameters analyzed were: tidal volume, minute volume, maximal inspiratory pressure, maximal expiratory pressure, oxygen saturation, heart rate and respiratory frequency. RESULTS: Sixty-seven patients submitted to myeloablative hematopoietic stem cell transplantation were included in this study. Among these, thirty-nine were evaluated and randomized in the two groups. There were significant differences between the groups for tidal volume at D+2 (p-value = 0.007) and maximal inspiratory pressure (p-value = 0.03), maximal expiratory pressure (p-value = 0.03) and tidal volume (p-value = 0.004) at D+7. CONCLUSIONS: On comparing Group A with Group B, the authors concluded that the protocol of respiratory physiotherapy applied in this study resulted in an improvement in ventilation and in respiratory muscle strength of patients submitted to hematopoietic stem cell transplantation. Associação Brasileira de Hematologia e Hemoterapia 2012 /pmc/articles/PMC3459632/ /pubmed/23049417 http://dx.doi.org/10.5581/1516-8484.20120047 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bom, Eliane Aparecida
de Souza, Clarissa Vasconcelos
Thiesen, Rosana Almeida da Silva
Miranda, Eliana Cristina Martins
de Souza, Carmino Antonio
Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title_full Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title_fullStr Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title_full_unstemmed Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title_short Evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
title_sort evaluation of respiratory conditions in early phase of hematopoietic stem cell transplantation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459632/
https://www.ncbi.nlm.nih.gov/pubmed/23049417
http://dx.doi.org/10.5581/1516-8484.20120047
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