Genetic Variation in the TNF Gene Is Associated with Susceptibility to Severe Sepsis, but Not with Mortality

BACKGROUND: Tumor necrosis factor (TNF) and TNF receptor superfamily (TNFR)-mediated immune response play an essential role in the pathogenesis of severe sepsis. Studies examining associations of TNF and lymphotoxin-α (LTA) single nucleotide polymorphisms (SNPs) with severe sepsis have produced conf...

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Detalles Bibliográficos
Autores principales: Song, Zhenju, Song, Yuanlin, Yin, Jun, Shen, Yao, Yao, Chenling, Sun, Zhan, Jiang, Jinjun, Zhu, Duming, Zhang, Yong, Shen, Qinjun, Gao, Lei, Tong, Chaoyang, Bai, Chunxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459853/
https://www.ncbi.nlm.nih.gov/pubmed/23029405
http://dx.doi.org/10.1371/journal.pone.0046113

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