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PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance
Lipid and protein tyrosine phosphatase, phosphatase and tension homologue (PTEN), is a widely known negative regulator of insulin/phosphoinositide 3-kinase signaling. Down-regulation of PTEN is thus widely documented to ameliorate insulin resistance in peripheral tissues such as skeletal muscle and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Cell Biology
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459864/ https://www.ncbi.nlm.nih.gov/pubmed/22875989 http://dx.doi.org/10.1091/mbc.E12-05-0337 |