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Downregulation of Genes Involved in Metabolism and Oxidative Stress in the Peripheral Leukocytes of Huntington's Disease Patients
BACKGROUND: Huntington's disease (HD) is caused by expanded CAG repeats encoding a polyglutamine tract in the huntingtin (HTT) protein. A number of differentially-expressed protein molecules have been identified in striatum of HD animal models. Here we examined if the expression changes could b...
Autores principales: | Chang, Kuo-Hsuan, Chen, Yi-Chun, Wu, Yih-Ru, Lee, Wan-Fen, Chen, Chiung-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459918/ https://www.ncbi.nlm.nih.gov/pubmed/23029535 http://dx.doi.org/10.1371/journal.pone.0046492 |
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