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Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers
The human cysteine dioxygenase 1 (CDO1) gene is a non-heme structured, iron-containing metalloenzyme involved in the conversion of cysteine to cysteine sulfinate, and plays a key role in taurine biosynthesis. In our search for novel methylated gene promoters, we have analyzed differential RNA expres...
Autores principales: | Brait, Mariana, Ling, Shizhang, Nagpal, Jatin K., Chang, Xiaofei, Park, Hannah Lui, Lee, Juna, Okamura, Jun, Yamashita, Keishi, Sidransky, David, Kim, Myoung Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459978/ https://www.ncbi.nlm.nih.gov/pubmed/23028699 http://dx.doi.org/10.1371/journal.pone.0044951 |
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