In search of a tolerance-induction strategy for cow's milk allergies: significant reduction of beta-lactoglobulin allergenicity via transglutaminase/cysteine polymerization: Allergoid generation by polymerization

OBJECTIVE: To explore the use of β-lactoglobulin polymerized using microbial transglutaminase and heating to identify whether protein polymerization could reduce in vivo allergenicity and maintain in vitro and ex vivo immunoreactivity for use in tolerance-induction protocols. METHODS: Based on previ...

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Detalles Bibliográficos
Autores principales: Olivier, Celso Eduardo, dos Santos Lima, Regiane Patussi, Pinto, Daiana Guedes, dos Santos, Raquel Acácia Pereira Gonçalves, da Silva, Grayce Katlen Moreno, Lorena, Sônia Letícia Silva, Villas-Boas, Mariana Battaglin, Netto, Flávia Maria, de Lima Zollner, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460020/
https://www.ncbi.nlm.nih.gov/pubmed/23070344
http://dx.doi.org/10.6061/clinics/2012(10)09

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