Liver inflammation in a mouse model of Th1 hepatitis despite the absence of invariant NKT cells or the Th1 chemokine receptors CXCR3 and CCR5

The specific mechanisms that mediate CD4(+) T cell mediated liver injury have not been fully elucidated. CD4(+) invariant NKT (iNKT) cells are required for liver damage in some mouse models of hepatitis, while the chemokine receptors CXCR3 and CCR5 are considered dominant Th1 chemokine receptors inv...

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Detalles Bibliográficos
Autores principales: Cripps, James G., Celaj, Stela, Burdick, Marie, Strieter, Robert M., Gorham, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460069/
https://www.ncbi.nlm.nih.gov/pubmed/22906987
http://dx.doi.org/10.1038/labinvest.2012.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460069/
https://www.ncbi.nlm.nih.gov/pubmed/22906987
http://dx.doi.org/10.1038/labinvest.2012.104

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