Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

Abnormal replication timing has been observed in cancer but no study has comprehensively evaluated this misregulation. We generated genome-wide replication-timing profiles for pediatric leukemias from 17 patients and three cell lines, as well as normal B and T cells. Nonleukemic EBV-transformed lymp...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryba, Tyrone, Battaglia, Dana, Chang, Bill H., Shirley, James W., Buckley, Quinton, Pope, Benjamin D., Devidas, Meenakshi, Druker, Brian J., Gilbert, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460179/
https://www.ncbi.nlm.nih.gov/pubmed/22628462
http://dx.doi.org/10.1101/gr.138511.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460179/
https://www.ncbi.nlm.nih.gov/pubmed/22628462
http://dx.doi.org/10.1101/gr.138511.112

Ejemplares similares