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Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

Abnormal replication timing has been observed in cancer but no study has comprehensively evaluated this misregulation. We generated genome-wide replication-timing profiles for pediatric leukemias from 17 patients and three cell lines, as well as normal B and T cells. Nonleukemic EBV-transformed lymp...

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Detalles Bibliográficos
Autores principales:	Ryba, Tyrone, Battaglia, Dana, Chang, Bill H., Shirley, James W., Buckley, Quinton, Pope, Benjamin D., Devidas, Meenakshi, Druker, Brian J., Gilbert, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460179/ https://www.ncbi.nlm.nih.gov/pubmed/22628462 http://dx.doi.org/10.1101/gr.138511.112

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