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Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations

X chromosome inactivation (XCI) achieves dosage balance in mammals by repressing one of two X chromosomes in females. During XCI, the long noncoding Xist RNA and Polycomb proteins spread along the inactive X (Xi) to initiate chromosome-wide silencing. Although inactivation is known to commence at th...

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Detalles Bibliográficos
Autores principales:	Pinter, Stefan F., Sadreyev, Ruslan I., Yildirim, Eda, Jeon, Yesu, Ohsumi, Toshiro K., Borowsky, Mark, Lee, Jeannie T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460182/ https://www.ncbi.nlm.nih.gov/pubmed/22948768 http://dx.doi.org/10.1101/gr.133751.111

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