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Transcription factor redundancy and tissue-specific regulation: Evidence from functional and physical network connectivity
Two major transcriptional regulators of Caenorhabditis elegans bodywall muscle (BWM) differentiation, hlh-1 and unc-120, are expressed in muscle where they are known to bind and regulate several well-studied muscle-specific genes. Simultaneously mutating both factors profoundly inhibits formation of...
Autores principales: | Kuntz, Steven G., Williams, Brian A., Sternberg, Paul W., Wold, Barbara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460186/ https://www.ncbi.nlm.nih.gov/pubmed/22730465 http://dx.doi.org/10.1101/gr.133306.111 |
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