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Quantification of PtdInsP(3) molecular species in cells and tissues by mass spectrometry

Class I phosphoinositide-3-kinase (PI3K) isoforms generate the intracellular signalling lipid, phosphatidylinositol(3,4,5)trisphosphate (PtdIns(3,4,5)P(3)). PtdIns(3,4,5)P(3) regulates major aspects of cellular behavior and the use of both genetic and pharmacological intervention has revealed import...

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Detalles Bibliográficos
Autores principales: Clark, Jonathan, Anderson, Karen E., Juvin, Veronique, Smith, Trevor S., Karpe, Fredrik, Wakelam, Michael J.O., Stephens, Len R., Hawkins, Phillip T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460242/
https://www.ncbi.nlm.nih.gov/pubmed/21278744
http://dx.doi.org/10.1038/nmeth.1564