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Quantification of PtdInsP(3) molecular species in cells and tissues by mass spectrometry
Class I phosphoinositide-3-kinase (PI3K) isoforms generate the intracellular signalling lipid, phosphatidylinositol(3,4,5)trisphosphate (PtdIns(3,4,5)P(3)). PtdIns(3,4,5)P(3) regulates major aspects of cellular behavior and the use of both genetic and pharmacological intervention has revealed import...
Autores principales: | Clark, Jonathan, Anderson, Karen E., Juvin, Veronique, Smith, Trevor S., Karpe, Fredrik, Wakelam, Michael J.O., Stephens, Len R., Hawkins, Phillip T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460242/ https://www.ncbi.nlm.nih.gov/pubmed/21278744 http://dx.doi.org/10.1038/nmeth.1564 |
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