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Lymphatic endothelial cells - key players in regulation of tolerance and immunity

The lymphatic vasculature provides routes for dendritic cell and lymphocyte migration into and out of lymph nodes. Lymphatic endothelial cells (LEC) control these processes by expression of CCL21, sphingosine-1-phosphate, and adhesion molecules. LEC express MHC-I and MHC-II, but not costimulatory mo...

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Detalles Bibliográficos
Autores principales: Tewalt, Eric F., Cohen, Jarish N., Rouhani, Sherin J., Engelhard, Victor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460259/
https://www.ncbi.nlm.nih.gov/pubmed/23060883
http://dx.doi.org/10.3389/fimmu.2012.00305