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The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study
BACKGROUND: Many randomized trials involve measuring a continuous outcome - such as pain, body weight or blood pressure - at baseline and after treatment. In this paper, I compare four possibilities for how such trials can be analyzed: post-treatment; change between baseline and post-treatment; perc...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34605/ https://www.ncbi.nlm.nih.gov/pubmed/11459516 http://dx.doi.org/10.1186/1471-2288-1-6 |