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Kaposi's Sarcoma Herpesvirus K15 Protein Contributes to Virus-Induced Angiogenesis by Recruiting PLCγ1 and Activating NFAT1-dependent RCAN1 Expression
Kaposi's Sarcoma (KS), caused by Kaposi's Sarcoma Herpesvirus (KSHV), is a highly vascularised angiogenic tumor of endothelial cells, characterized by latently KSHV-infected spindle cells and a pronounced inflammatory infiltrate. Several KSHV proteins, including LANA-1 (ORF73), vCyclin (OR...
Autores principales: | Bala, Kiran, Bosco, Raffaella, Gramolelli, Silvia, Haas, Darya A., Kati, Semra, Pietrek, Marcel, Hävemeier, Anika, Yakushko, Yuri, Singh, Vivek Vikram, Dittrich-Breiholz, Oliver, Kracht, Michael, Schulz, Thomas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460623/ https://www.ncbi.nlm.nih.gov/pubmed/23028325 http://dx.doi.org/10.1371/journal.ppat.1002927 |
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