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Identification of Alternatively Translated Tetherin Isoforms with Differing Antiviral and Signaling Activities
Tetherin (BST-2/CD317/HM1.24) is an IFN induced transmembrane protein that restricts release of a broad range of enveloped viruses. Important features required for Tetherin activity and regulation reside within the cytoplasmic domain. Here we demonstrate that two isoforms, derived by alternative tra...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460627/ https://www.ncbi.nlm.nih.gov/pubmed/23028328 http://dx.doi.org/10.1371/journal.ppat.1002931 |